FZD1 抗体
Quick Overview for FZD1 抗体 (ABIN2431911)
抗原
See all FZD1 (Fzd1) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human FZD1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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注意事项
- Avoid freeze / thaw cycles.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store at -20°C (regular) and -80°C (long term).
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- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
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别名
- FZD1
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背景
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Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
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分子量
- Calculated MW: 71 kDa
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途径
- WNT signaling, Asymmetric Protein Localization
抗原
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